Two synthetic routes to bis(1-methyl-imidazole-2-thione)methane and bis(1-benzyl-imidazole-2-thione)methane complexes including sulfur atom insertion into copper−NHC bonds

Design and Synthesis of 2-Methyl and 2-Methyl-4-Nitro Imidazole Derivatives as Antifungal Agents

      Two series (a and b) of N- substituted heteroaromatic compounds related to clotrimazole were synthesized. Imidazole ring of the clotrimazole was replaced by 2-methylimidazole in series a, and by 2-methyl-4-nitroimidazole in series b. O-cholortrityl moiety of clotrimazole was also replaced by trityl, mono or dimethoxy trityl. Chemical structures...

design and synthesis of 2-methyl and 2-methyl-4-nitro imidazole derivatives as antifungal agents

two series (a and b) of n- substituted heteroaromatic compounds related to clotrimazole were synthesized. imidazole ring of the clotrimazole was replaced by 2-methylimidazole in series a, and by 2-methyl-4-nitroimidazole in series b. o-cholortrityl moiety of clotrimazole was also replaced by trityl, mono or dimethoxy trityl. chemical structures of all the new compounds were confirmed by spec-tr...

1-Benzyl-2-(4-chloro­phen­yl)-4,5-di­phenyl-1H-imidazole

The mol-ecular conformation of the title compound, C(28)H(21)ClN(2), is stabilized by an intra-molecular C-H⋯N hydrogen bond. It has many pharmacological properties, such as being an inhibitor of P38 MAP Kinase, and can play an important role in biochemical processes.

genotoxic effects of 2-methoxy and 2-methyl benzofuran phenylmethyl imidazole on mcf-7 cell line

2-Phenyl-1H-imidazole

In the title compound, C(9)H(8)N(2), a mirror plane lies perpendicular to the phenyl and imidazole rings and passes through the bridging C-C bond, so that the imidazole ring is disordered over two sites about the mirror plane with the equal site occupancy; the asymmetric unit contains one half-mol-ecule. In the crystal, adjacent mol-ecules are linked via N-H⋯N hydrogen bonds.